Identifying The Root Of The Problem

What causes chronic neurodegeneration after traumatic brain injury?

Traumatic brain injuries (TBIs) are a major public health concern, affecting millions of people worldwide. TBIs can result in a wide range of disabilities, including cognitive impairment, physical impairments, and emotional problems. Chronic neurodegeneration is a common complication of TBI and can lead to further disability and even death.

The exact cause of chronic neurodegeneration after TBI is not fully understood, but it is thought to be caused by a combination of factors, including:

Primary injury: This is the initial damage to the brain that occurs at the time of the injury.

Secondary injury: This is the damage that occurs after the primary injury and is caused by a number of factors, including inflammation, oxidative stress, and excitotoxicity.

What are the consequences of chronic neurodegeneration after traumatic brain injury?

Chronic neurodegeneration after TBI can lead to a number of disabilities, including:

Cognitive impairment: This can range from mild memory problems to severe dementia.

Physical impairments: This can include difficulty with movement, balance, and coordination.

Emotional problems: This can include depression, anxiety, and irritability.

Increased risk of death: People with chronic neurodegeneration after TBI are at an increased risk of death from all causes, including heart disease, cancer, and respiratory problems.